Application of hypofractionated conformal radiotherapy in non-small cell lung cancer
10.3760/cma.j.issn.1673-422X.2011.05.017
- VernacularTitle:大分割适形放射治疗在非小细胞肺癌中的应用
- Author:
Liming SHENG
;
Yaping XU
;
Shenglin MA
- Publication Type:Journal Article
- Keywords:
Carcinoma,non-small-cell lung;
Radiotherapy,conformal
- From:
Journal of International Oncology
2011;38(5):374-376
- CountryChina
- Language:Chinese
-
Abstract:
Hypofractionated conformal radiotherapy is capable to deliver much higher doses to the cancer than is possible with standard techniques. Recently there is data suggesting that the early stage nonsmall cell lung cancer ( NSCLC) which is not suitable to surgery is likely to benefit from this regimen, with low lung toxicity. Manyphase Ⅰ-Ⅱ studies showed that the patients with locally advanced NSCLC are well-tolerated to hypofractionated conformal radiotherapy. The model of radio-physic and relative clinical studies suggest that hy-pofractionation would not increase the risk of radiation pneumonitis compared to standard therapy.