Impact of past Toxoplasma gondii infection on the fetus during pregnancy
- VernacularTitle:弓形虫既往感染在孕期内对胎儿的影响
- Author:
Qian XU
;
Haiyong HUA
- Publication Type:Journal Article
- Keywords:
Toxoplasma gondii;
Vertical transmission;
Pregnancy
- From:
Chinese Journal of Schistosomiasis Control
2010;22(2):187-188
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss the activity of Toxoplasma gondii and its impact on fetus during pregnancy.Methods Sixty -eight pregnant women whose IgG was positive and IgM was negative for anti - Toxoplasma gondii antibodies were chosen.Their serum and umbilical blood were tested for IgG,IgM,CAg (by ELISA) and DNA (by PCR) of Toxoplasma gondii.The infections of placental samples were tested by the direct smear,homogenate smear and PCR.Results There were 28 positive cases of Toxoplasma gondii IgG antibodies in cord blood,and the vertical transmission rate of IgG in placenta was 41.2%.There were 6 positive cases of Toxoplasma gondii DNA in cord blood,and the incidence of intrauterine infection was 8.8%.There were 9 positive cases of Toxoplasma gondii DNA in placental tissues,and the incidence of intrauterine infection was 13.2%.Conclusions Past Toxoplasma gondii infection during pregnancy may lead to vertical transmission between the mother and infant.
