The effects of fish oil fat emulsion on nutritional status and humoral immunity in postoperative patients suffering from gastrointestinal malignancy
- VernacularTitle:鱼油脂肪乳对胃肠道恶性肿瘤病人术后营养状况和体液免疫的影响
- Author:
Cheng LU
;
Wenyue WANG
;
Weizhao PENG
;
Xueying YU
- Publication Type:Journal Article
- Keywords:
Gastrointestinal malignancy;
ω-3 fish oil fat emulsion;
Parenteral nutrition;
Humoral immunity
- From:Parenteral & Enteral Nutrition
2009;16(6):324-327
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the effects of ω-3 fish oil fat emulsion on nutritional status and humoral immunity in postoperative patients suffering from gastrointestinal malignancy. Methods: Thirty patients of gastrointestinal malignancy were randomly divided into study group (n = 15) and control group (n = 15). All the patients were assigned to receive total parenteral nutrition with the equal nitrogen and calory,and those in study group received fish oil fat emulsion additionally. Liver and renal function, blood lipid, haemoglobin, albumin, transferrin, total lymphocyte count (TLC) , B lymphocyte subsets (B1, B2), immunoglobin(IgG, IgM, IgA) and complement(C3, C4) were determined preoperatively and 1, 6d postoperatively. Results: There were no significant differences in liver and renal function and blood lipid on postoperative day 6 versus preoperation in all the two groups. TLC, IgG, IgM, C3 on postoperative day 6 were siginificantly higher in the study group(P < 0. 05). Haemoglobin, albumin, transferrin and B lymphocyte subsets were not significantly different between the two groups. Conclusion: Fish oil fat emulsion treatment was safe and tolerated, and could improve the humoral immunity in patients.
