The effect of omega-3 polyunsaturated fatty acids on elder patients after gastric cancer operation
- VernacularTitle:ω-3多不饱和脂肪酸在老年胃癌病人术后肠外营养中的应用
- Author:
Yuzhe WEI
;
Hongjiang SONG
;
Jia WANG
;
Tie WANG
;
Xiuwen LAN
;
Yingwei XUE
- Publication Type:Journal Article
- Keywords:
Gastric cancer;
ω-3 polyunsaturated fatty acids;
Immune function
- From:
Parenteral & Enteral Nutrition
2009;16(6):328-331
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the clinical effect of ω-3 polyunsaturated fatty acids (ω-3 PUFA) on elder patients after gastric cancer radical operation. Methods: Forty patients were randomly divided into experimental group (EG) and control group(CG). The patients of CG were treated with hypocaloric and lower nitrogen parenteral nutrition, and those in EG received ω-3 PUFA additionally. The nutrition index, immune function, liver function, inflammatory reaction and complications were compared. Results: The rate of complications significantly decreased in the EG (20% vs 5% , χ~2 = 3. 958, P < 0. 05). There were no significant differences in albumn and hemoglobin between the two groups (P > 0. 05). The level of prealbumin was significantly increased in the EG. The humoral immunity and cellular immunity were higher in the EG than those in the CG. IL-6, TNF-α and CRP levels on postoperative d5 were significantly depressed in the EG. Conclusion: Postoperative supplementation of ω-3 PUFA may have a favorable effect on the outcomes in elder gastric cancer patients.
