The alteration of intestinal flora in patients with reconstruction of the upper gastrointestinal tract
- VernacularTitle:上消化道重建术后肠腔菌群的改变
- Author:
Dongguang NIU
;
Lianan DING
;
Hui LI
;
Tao ZHANG
;
Hongchun FANG
- Publication Type:Journal Article
- Keywords:
Intestinal flora;
Bacterial translocation;
Gastrointestinal tract
- From:
Parenteral & Enteral Nutrition
2009;16(4):228-230
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate changes in species and amounts of intestinal flora after reconstruction of upper digestive tract, and the relationship with the infective complications.Methods: 52 patients with advanced malignancy being performed reconstruction of upper gastrointestinal tract was prospectively observed .The species of bacteria and counts of the colony forming units(CFU) were measured from juice taking from the upper jejunum through nasointestinal tube during operation, the second day and the fifth day after operation. Meanwhile, the plasma endotoxin concentration was determined with the modified chromogenic limulus assay.Results: There weren't significant changes of intestinal flora in species and amounts between groups (P>0.05.) No any signs of bacterial translocation were seen. There was no significant difference for the level of plasma endotoxin between groups.Conclusion: There is no disorder of intestinal flora and bacterial translocation during the perioperative period after upper digestive tract reconstruction successfully.