Interactions between Immune Cells and Tumor Cells.
10.11106/jkta.2013.6.2.96
- Author:
Sun Wook CHO
1
Author Information
1. Department of Internal Medicine, Seoul National University College of Medicine, Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea. swchomd@snu.ac.kr
- Publication Type:Review
- Keywords:
Tumor microenvironment;
Tumor associated macrophages (TAM);
Myeloid derived suppressor cells (MDSC);
Cancer immunology
- MeSH:
Allergy and Immunology;
Endothelial Cells;
Fibroblasts;
Humans;
Immune System;
Macrophages;
Tumor Microenvironment
- From:Journal of Korean Thyroid Association
2013;6(2):96-100
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Tumor microenvironment is defined as a heterogeneous complex composed of cancer cells, vascular endothelial cells, fibroblasts, and diverse immune cells. Cancer immunology is the study of interactions between the immune system and cancer cells which is applied to develop therapeutic strategies for human cancers. This review focused on tumor promoting myeloid derived cells such as tumor associated macrophages (TAM) and myeloid derived suppressor cells (MDSC) and their therapeutic applications.
