Association of serum levels of HDL-C,LDL-C with lymphatic metastasis and clinical stage in gastric cancer
10.3760/cma.j.issn.1006-9801.2011.07.004
- VernacularTitle:血清脂蛋白与胃癌淋巴结转移及肿瘤分期的关系
- Author:
Daguang FAN
;
Huanfang LIANG
;
Jianfang MA
- Publication Type:Journal Article
- Keywords:
Gastric carcinoma;
HDL-C;
Lymphatic metastasis
- From:
Cancer Research and Clinic
2011;23(7):447-449
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the correlation of serum levels of HDL-C,LDL-C with clinical stage and lynlphatic metastasis in gastric malignant tumors. Methods Preoperative serum levels of HDL-C and LDL-C were retrospectively analyzed in 114 gastric cancer patients who were diagnosed by pathology.Results Serum, levels of HDL-C showed a remarkable correlation with tumor differentiation,lymphatic metastasis and the diameter of tumor in gastric cancer (P＜0.05).The lower serum levels of HDL-C were significantly observed in gastric cancer patients with TNM Ⅲ and IV stage,compared with those with TNM Ⅰ and Ⅱ stage (P＜0.05). Conclusion Preoperative serum levels of HDL-C might be a useful biomarker of lymphatic metastasis and advanced stage of gastric cancer.
