Identification of chemical constituents in qiliqiangxin capsule by UPLC-Q-TOF/MS(E).
- Author:
Liping KANG
;
Yang ZHAO
;
Heshui YU
;
Yixun LIU
;
Chengqi XIONG
;
Dawei TAN
;
Jiming JIA
;
Hongtao WANG
;
Shuyan TIAN
;
Baiping MA
- Publication Type:Journal Article
- From:
Acta Pharmaceutica Sinica
2011;46(10):1231-6
- CountryChina
- Language:Chinese
-
Abstract:
In order to clarify the chemical constituents in Qiliqiangxin capsule, a rapid ultra-performance liquid chromatography/orthogonal acceleration time-of-flight mass spectrometry (UPLC-Q-TOF/MS(E)) method was established. Forty peaks were identified on line using this method. The herbal sources of these peaks were assigned. The results implied that triterpenoid saponins, flavonoid glycosides, C21-steroids and phenolic acids were included in the main components of Qiliqiangxin capsule. The method is simple and rapid for elucidation of the constituents of Qiliqiangxin capsule and the results are useful for the quality control of Qiliqiangxin capsule.
