Hepatoprotective effects of Protecliv in the experiments
- Author:
Vu Manh Hung
- Publication Type:Journal Article
- Keywords:
Hepatoprotection
- MeSH:
Protective Agents;
Liver;
Animal Experimentation
- From:Journal of Practical Medicine
2005;10():17-20
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
Protecliv is one of products of the National Project-2003 were tested before approval. This product was manufactored by The Central Pharmaceutical Company No1. The role of the Protecliv were investigated in protection against INH and RIF-induced hepatotoxicity in young rats. All drugs were administered orally in suspension form over one week. These results suggested that , INH-RIF-induced hepatotoxicity can be prevented by Protecliv at the two levels of the dose. The significant hepatoprotective dose of this compound was 250 and 500mg/kg wb/day (p<0.01) according the level of the used dose.
