Progress of the causes of infantile cholestasis
10.3760/cma.j.issn.1673-4408.2011.02.020
- VernacularTitle:婴儿胆汁淤积症的病因研究进展
- Author:
Lu YANG
- Publication Type:Journal Article
- Keywords:
Cholestasis;
Infantile;
Etiology
- From:
International Journal of Pediatrics
2011;38(2):158-161
- CountryChina
- Language:Chinese
-
Abstract:
Infantile cholestasis is a syndrome caused by multiple factors with conjugated hyperbilirubinemia for clinical characteristics. The etiologic factors include infection, poisoning, inherited metabolic defects and bile duct abnormalities. Infection, biliary atresia accounts for more than half of cholestasis children. Recently, the new causes have been recognized, for example citrin deficiency, Alagille syndrome,progressive familial cholestasis symptoms caused by different causes are similar to biliary atresia, but the prognosis and treatment are quite different. If misdiagnosed, the condition will exacerbate. Understanding the various causes plays an important role for the early diagnosis and differential diagnosis of infantile cholestasis.
