Caspase-9 and ischemic cerebrovascular disease
10.3760/cma.j.issn.1673-4165.2011.02.014
- VernacularTitle:胱冬酶-9与缺血性脑血管病
- Author:
Xiongzi CHEN
;
Weiduan ZHUANG
- Publication Type:Journal Article
- Keywords:
Caspase 9;
Apoptosis;
Brain ischemia;
Cerebrovascular disorders
- From:
International Journal of Cerebrovascular Diseases
2011;19(2):147-150
- CountryChina
- Language:Chinese
-
Abstract:
Caspases are a group of enzymes mainly for the execution of apoptosis.In recent years,studies have shown that caspases participate in the occurrence and development of many diseases,especially tumors and nervous system diseases.Of those,caspase-9 is one of the most important initiating molecules.This article reviews the structural characteristics,activation and regulation of caspase-9,its regulation mechanism of apoptosis,and briefly describes its relation with ischemic cerebrovascular disease.
