Progress of immunology in epilepsy
10.3760/cma.j.issn.1673-4408.2011.02.008
- VernacularTitle:癫(癎)的免疫学研究进展
- Author:
Chun LI
- Publication Type:Journal Article
- Keywords:
Epilepsy;
Humoral immunity;
Cellular immunity;
Antiepileptic drugs
- From:
International Journal of Pediatrics
2011;38(2):121-124
- CountryChina
- Language:Chinese
-
Abstract:
Epilepsy is the most common neurological disease in children. Nowadays, the functional disturbances of the immune system, both humeral and cell-mediated immunity, have been detected more often in patients with epilepsy than in normal individuals, which include changes of cytokine, autoantibody and immunoglobulin in humoral immunity, and changes of lymphocyte subset, lymphocyte hyperpalsy zone and nature killer cell in cellular immunity. Not only the peripheral blood of the patients is abnormal, but also the cerebrospinal fluid can be found unusual. Some antiepileptic drugs (AEDs) can exert an effect on the function of immune system as well. Elucidation of connections between epileptogenesis, immunology and effectiveness of antiepileptic drugs therapy is to be explored.
