Research progress in gastric cancer stem cell
10.3760/cma.j.issn.1673-422X.2011.01.017
- VernacularTitle:胃癌干细胞研究进展
- Author:
Dongyan CAI
;
Dong HUA
- Publication Type:Journal Article
- Keywords:
Stomach neoplasms;
Neoplastic stem cells
- From:
Journal of International Oncology
2011;38(1):51-53
- CountryChina
- Language:Chinese
-
Abstract:
Cancer stem cells(CSCs) are a group of tumor cells with stem cell-like properties such as infinite self-renewal and multi-differentiation potential. Accumulating evidence strongly indicates the presence of cancer stem cells in a variety of solid tumors. Although rare, CSCs play important roles in tumor initiation, progression, recurrence and metastasis. Research of gastric cancer stem cells is still in its infancy. Specific surface markers of gastric CSC are yet to be identified. Active researches are currently underway to investigate the existence and source of CSC in gastric cancer.