Recombinant-adeno-associated viral vector-mediated gene therapy for cardiovascular diseases
10.3969/j.issn.1672-7347.2011.02.016
- VernacularTitle:重组腺相关病毒载体在心血管疾病基因治疗中的应用
- Author:
Meizhen ZHANG
;
Hong YUAN
;
Zhijun HUANG
;
Fang HU
- Publication Type:Journal Article
- Keywords:
recombinant-adeno-associated virus vector;
cardiovascular disease;
gene therapy
- From:
Journal of Central South University(Medical Sciences)
2011;36(2):178-184
- CountryChina
- Language:Chinese
-
Abstract:
Adeno-associated virus is a kind of DNA defective parvovirus which is non-pathogenic. Recombinant-adeno-associated virus vector comes from wild-type non-pathogenic adeno-associated virus and is highly secure, and it also has the advantages of broad host range. Recombinant-adeno-associated virus vector has become a hot spot for gene therapy and is widely used in gene therapy for cardiovascular diseases, especially for hypertension, heart failure, arteriosclerosis, and myocardial infarction.
