hMSH6 polymorphisms and cancer susceptibility
10.3760/cma.j.issn.1673-422X.2011.04.001
- VernacularTitle:hMSH6基因多态与肿瘤易感性
- Author:
Wei LIU
;
Zhiqiang LING
;
Weimin MAO
- Publication Type:Journal Article
- Keywords:
Neoplasms;
Polymorphism,genetic;
Gene expression regulation
- From:
Journal of International Oncology
2011;38(4):243-245
- CountryChina
- Language:Chinese
-
Abstract:
hMSH6 is one of the most important members in the mismatch repair family. Its polymorphism is closely related to the pathogenesis and development of neoplasm, particularly in colorectal cancer and endometrial cancer. Moreover, it has been suggested to play a more important role in endometrial cancer compared with hMLH1 and hMSH2.
