Recent advances in eukaryotic elongation factor 1 alpha 2 and tumor
10.3760/cma.j.issn.1673-422X.2011.03.005
- VernacularTitle:真核延伸因子1A2与肿瘤
- Author:
Peng ZHANG
;
Kaixiong TAO
- Publication Type:Journal Article
- Keywords:
Neoplasms;
eEF1A2 protein
- From:
Journal of International Oncology
2011;38(3):176-179
- CountryChina
- Language:Chinese
-
Abstract:
Eukaryotic elongation factor 1 alpha 2(eEF1 A2),which plays a role in the translational elongation process,is normally expressed only in the heart,brain and skeletal musle,but recent studies found it is highly expressed in a variety of tumors and closely related to the oncogenesis and development of tumor.As the signal transduction mechanism is clarified,eEF1A2 is likely to become a novel target for tumor therapy.