Detection of prolactin-inducible protein expression in patients with breast cancer micro-metastasis
10.3760/cma.j.issn.1673-422X.2011.03.015
- VernacularTitle:乳腺癌微转移中泌乳素诱导蛋白表达的检测
- Author:
Guojing ZHANG
;
Xiaodong XIE
;
Zhaozhe LIU
- Publication Type:Journal Article
- Keywords:
Breast neoplasms;
Neoplasm metastasis;
Tumor markers,biological
- From:
Journal of International Oncology
2011;38(3):210-213
- CountryChina
- Language:Chinese
-
Abstract:
Prolactin-inducible protein(PIP)is regarded as a kind of specific tumor marker,and detecting the expression of PIP from breast cancer tissues,metastatic lymph nodes and peripheral blood can find breast cancer micro-metastasis effectively.Some technologies such as immunohistochemistry,reverse transcription polymerase chain reaction and so on can detect PIP sensitivily.Recently,these technologies have been used in some clinical and basic studies.Detection rate of breast cancer micro-metastasis is improved effectively when PIP is combined with other tumor makers,especially mammag-lobin and cytokeratin 19.
