Advance in differential proteomics of high expression of gastrin-based colorectal neoplasms research
10.3760/cma.j.issn.1673-422X.2011.03.018
- VernacularTitle:胃泌素高表达型大肠癌差异蛋白质组学的研究进展
- Author:
Honghai XU
;
Pei WU
- Publication Type:Journal Article
- Keywords:
Proteomics;
Colorectal Neoplasms;
Gastrins
- From:
Journal of International Oncology
2011;38(3):216-220
- CountryChina
- Language:Chinese
-
Abstract:
The abnormal expression of gastrins and their receptors have close relationship with the occurrenceand the development of some colorectal neoplasms.The high expression of gastrins and their receptors promote colorectal neoplasms cell proliferation and inhibit apoptosis.The biological behavior is mainly rely on the abnormal expression of protein.Using differential proteomics can screen differential expression protein of high expression of gastrin-based colorectal neoplasms in the occurrence and development process,and then with the regulation of specific proteins to achieve the prevention and treatment of colorectal neoplasms purposes.
