Status and prospects of application of nude mouse models in research of human bladder tumor
10.3760/cma.j.issn.1673-422X.2011.01.023
- VernacularTitle:裸鼠模型在人膀胱癌中的实验研究现状及展望
- Author:
Dechun ZHU
;
Lucheng LIU
;
Dusu WEN
- Publication Type:Journal Article
- Keywords:
Urinary bladder neoplasms;
Disease models,animal
- From:
Journal of International Oncology
2011;38(1):70-73
- CountryChina
- Language:Chinese
-
Abstract:
Nude mouse bearing human bladder cancer exhibits similar growth characteristics as human bladder cancer and therfore is a good simulation model in the research of the biological behaviors of human bladder cancer. To explore the initiation, development, prognosis and biological behavior of human bladder cancer,and to develop intravesical biological agents and antitumor drugs with improved strategies for prevention and treatment of bladder cancer, it is essential to establish human bladder tumor-bearing nude mice for basic and clinical researches. This is a review of the current status of the application of human bladder tumor-bearing nude mice.
