Metastasis-related genes in human colorectal cancer:a literature review
10.3760/cma.j.issn.1673-4203.2011.02.014
- VernacularTitle:结直肠癌转移相关基因的研究现状
- Author:
Feng LIU
;
Guoxin LI
- Publication Type:Journal Article
- Keywords:
Colorectal neoplasms;
Neoplasm metastasis;
Genes
- From:
International Journal of Surgery
2011;38(2):117-120
- CountryChina
- Language:Chinese
-
Abstract:
Colorectal cancer is one of the most commonly seen malignant neoplasms in digestive tract.Most patients with colorectal cancer died of metastasis.The details of the metastasis-associated mechanisms are not elucidated completely.Recently,many genes that are involved in this course were detected.In this paper,the latest advances in those metastasis-associated genes and coding genes including C-myc,Ras,Her-2 ,p53,deleted in colorectal cancer gene (DDC),phosphatase and tensin homologue (PTEN),nm23 and other code genes,such as CD44,matrix metalloproteinases (MMPs) and mucins will be reviewed.
