Research progress in polymeric nanoparticle delivery systems for growth factor in tissue engineering
10.3760/cma.j.issn.1673-4181.2011.01.009
- VernacularTitle:基于组织工程应用的生长因子/高分子纳米粒子传递系统的研究进展
- Author:
Zhen XU
;
Haiyan XU
- Publication Type:Journal Article
- Keywords:
Nanoparticles;
Growth factor;
,Tissue engineering;
Delivery system
- From:
International Journal of Biomedical Engineering
2011;34(1):39-42
- CountryChina
- Language:Chinese
-
Abstract:
Effective loading and site-specific delivery of growth factors to regulate the cell growth on scaffold is one of the key issues of tissue engineering. Polymeric nanoparticle is one of the candidate carriers for carrying growth factors. This article attempts to introduce the biological characteristics of growth factors commonly used in tissue engineering, polymer materials for carrying the growth factors and the preparation of the nanoparticles and delivery systems. The advantages and disadvantages of different preparations are also discussed to facilitate the selection of the appropriate methods and materials. Relevant research progress and application potentials are discussed ss well.
