Clinical and imaging features of reversible posterior leukoencephalopathy syndrome:a retrospective study of 9 cases
10.3760/cma.j.issn.1673-4165.2011.02.006
- VernacularTitle:可逆性后部白质脑病综合征的临床和影像学特征:9例回顾性病例系列研究
- Author:
Meiling CHEN
;
Qinghua LI
;
Xiaohui LIN
- Publication Type:Journal Article
- Keywords:
Posterior leukoencephalopathy syndrome;
Magnetic resonance imaging;
Hypertension;
Age factors
- From:
International Journal of Cerebrovascular Diseases
2011;19(2):106-110
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical and imaging features of the reversible posterior leukoencephalopathy syndrome(RPLS).Methods The clinical and imagig data of 9 patients with RPLS were analyzed retrospectively.Results Among the patients,4(44%)were secondary to pregnancy-induced hypertension syndrome,1(11%)was second to short bowel syndrome,1(11% )was second to acute lymphoblastic leukemia,1( 11% )was second to IgA nephropathy,and 2(22%)were second to hypertensive encephalopathy.Their mean age of symptom onset was 23.4 ± 9.9 years.Their main clinical manifestations were headaches,seizures,blurred vision,and consciousness disturbance.Magnetic resonance imaging(MRI)showed symmetrical lesions of bilateral white matter in posterior brain.T1 weighted imaging and diffusion-weighted imaging showed low or isointense signal.T2 weighted imaging,fluid attenuated inversion recovery(FLAIR),and apparent diffusion coefficient(ADC)map showed high-intensity signal.The symptoms of the patients disappeared after the treatment.MRI reexamination showed that the lesions disappeared completely or almost completely.Conclusions The causes of RPLS were different.The imaging mainly showed the signal of vasogenic brain edema on the posterior white matter of the brain.After timely treatment,the symptorms and imaging features were improved rapidly.The patients with young-onset RPLS are their important clinical feature.[Key wonds]Posterior leukoencephalopathy syndrome;Magnetic resonance imaaging;Hypertension;Age factors were improved rapidly.The patients with young-onset RPLS are their important clinical feature.
