Progress of genetic etiology and detection method in congenital heart disease
10.3760/cma.j.issn.1673-4408.2011.02.029
- VernacularTitle:先天性心脏病遗传病因及检测方法研究进展
- Author:
Huijuan KAN
- Publication Type:Journal Article
- Keywords:
Congenital heart disease;
Gene;
PCR;
Comparative genomic hybridization
- From:
International Journal of Pediatrics
2011;38(2):188-191
- CountryChina
- Language:Chinese
-
Abstract:
The etiology of congenital heart disease (CHD) incluses genetic factors, environmental factors and maternal factors. The genetic etiology of CHD includes chromosomal abnormalities, single gene defects and multiple genetic defects. The genetic testing method of CHD has made great progress in karyotype analysis,fluorescence in situ hybridization, quantitative PCR, multiplex ligation dependent probe amplification, et al.
