miR-21 in gastrointestinal cancer: research progresses
10.3760/cma.j.issn.1673-422X.2011.01.015
- VernacularTitle:消化系统肿瘤中miR-21研究进展
- Author:
Jiamin YUAN
;
Zhiqiang LING
;
Weimin MAO
- Publication Type:Journal Article
- Keywords:
Digestive system neoplasms;
MicroRNAs
- From:
Journal of International Oncology
2011;38(1):45-48
- CountryChina
- Language:Chinese
-
Abstract:
miRNAs are endogenous short RNA molecules widely distributed in eukaryotic organisms.They are closely related to tumor development. One good example is miR-21. It is overexpressed in a variety of tumor tissues, suggesting that miR-21 may have significant carcinogenic activities and act as a oncogene.Many studies confirm that overexpression of miR-21 has great indication in the development, diagnosis, biological treatment and prognosis of gastrointestinal cancer.
