Angiographic features of infarct-related artery and the therapeutic efficacy of intravenous thrombolysis in patients with acute myocardial infarction
10.3760/cma.j.issn.1671-0282.2011.03.017
- VernacularTitle:急性心肌梗死溶栓效果与冠脉造影特征分析
- Author:
Hanchun WEN
;
Jijin ZHU
;
Lang LI
;
Liguang ZHU
;
Zhiheng ZEN
;
Kai HUANG
;
Yongwei YE
;
Shiwen LU
- Publication Type:Journal Article
- Keywords:
Acute Myocardial Infarction;
Intravenous Thrombolysis;
Reperfusion urokinase;
Coronary angiography
- From:
Chinese Journal of Emergency Medicine
2011;20(3):283-286
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the angiographic findings and the therapeutic effect of thrombolysis in AMI (acute myocardial infarction) patients. Method A retrospective study were carried out in consecutive eighty-four inpatients with AMI treated with intravenous thrombolysis and coronary angiography was taken within a week after illness onset from January 2000 to August 2007. The patients were divided into successful recanalization group and non-recanalization group. Single factor χ2 test and multi-factor logistic regression analysis were applied to observe the relationship among the angiographic features of IRA (infarct-related artery including the number of stnosis, the location of stenosis, the severity of stenosis and the morphological changes) and treatment effect of intravenous urokinase thrombolysis. Results (1) Single factor χ2 test showed that location and the extent of lesion of IRA were eligible to enter the logistic regression formula (P ＜ 0.05),whereas the number of lesions and the severity of IRA's stenosis were not eligible to enter the logistic regression formula (P ＞ 0. 05). (2) Multi-factor logistic regression analysis showed that the extent of lesion of IRA was the only factor that had a negative impact on the therapeutic effect of intravenous thrombolysis.Conclusions The study shows that the extent of lesion of IRA is the only factor that has a negative impact on the therapeutic effect of intravenous thrombolysis; The number, the location of lesion and the severity of stenosis of IRA have no impact on the therapeutic effect of intravenous thrombolysis in AMI.
