The effect of Nasal Healing Spraying Agent on red cell immune function in mice

VernacularTitle:鼻康喷雾剂对小鼠红细胞免疫功能的影响
Author: Jingjuan WANG ; Guijun ZHANG ; Shu YANG
Publication Type:Journal Article
Keywords: Nasal Healing Spraying Agent (NHSA); Test for red blood cellular immunity in mice; Immunoregulatory function
From: International Journal of Traditional Chinese Medicine 2011;33(3):212-213
CountryChina
Language:Chinese
Abstract: Objective To study the immunological regulation of Nasal Healing Spraying Agent (NHSA). Methods Test models were setup by irradiation. The models were administrated with NHSA by lavage and immune adherence of red cells was tested by chaplet experiment with blank and positive control. Results NHSA could increase Red Blood Cell-C3b Receptor Rosette (RBC-C3bRR) and reduce Red Blood Cell-Immune Complex Rosette (RBC-ICR) in mice. Compared with blank control group, the results in the high dose group and middle dose group were statistically significant (P<0.01). The result also showed that NHSA could elevate the quantity and activity of Red Blood Cell-C3b Receptor (RBC-C3bR) and reduce the Immune Complex (IC) to enhance the red cell immune function in mice effectively. Conclusion NHSA could elevate the RBC immunity function in mice and increase immunoregulatory function.