Study on preventive effect of volatile oil extracted from Foeniculum vulgare Mill. Seeds on postoperative intra-abdominal adhesions

VernacularTitle:小茴香挥发油对术后腹腔黏连的预防作用探讨
Author: Guangshou TENG ; Chengguo WANG ; Fengfeng MAO ; Yan ZHANG ; Xingyou LIU ; Peng YANG ; Lei SHI ; Manling LIU
Publication Type:Journal Article
Keywords: Foeniculurn vulgare Mill. Seeds; Volatile oil; Abdominal adhesion
From: International Journal of Traditional Chinese Medicine 2011;33(2):118-120
CountryChina
Language:Chinese
Abstract: Objective To study the preventive effect of volatile oil extracted from Foeniculum vulgare Mill. Seeds on the formation of postoperative intra-abdominal adhesion. Methods Thirty-eihgt SD rats were randomly divided into sham operation group (10), operation group (14) and volatile oil treated group (14):sham operation group was only operated by abdominal incision, the rest two groups were established animal model of abdominal adhesion by rubbing the procussus vermiformis of cecum with dry sterile gauze, clamping and scuffing abdominal wall. Half of rats were separately killed on day 7 and day 14 after surgery, respectively.The degree of adhesion was evaluated according to Phillips 5-scale grade and the feature of this model. Results The scores of intra-abdominal adhesion were significantly lower in the carbachol group than those in operation group both on 7 d and 14 d(P＜0.01 ). Conclusion Volatile oil extracted from Foeniculum vulgare Mill. Seeds may take a significant role in the prevention of postoperative abdominal adhesion in rats.