Molecular predictive biomarkers in non-small-cell lung cancer
10.3760/cma.j.issn.1673-422X.2011.04.012
- VernacularTitle:非小细胞肺癌分子预测标志物
- Author:
Qiuming WANG
;
Wanlan HUANG
;
Yingcheng LIN
- Publication Type:Journal Article
- Keywords:
Carcinoma,non-small-cell lung;
Tumor markers,biological;
Treatment outcome
- From:
Journal of International Oncology
2011;38(4):278-281
- CountryChina
- Language:Chinese
-
Abstract:
With the development of phamacogenomic and molecular biology, it has been revealed that the curative effect of non-small-cell lung cancer (NSCLC) is closely related to tumor molecular markers. Predictive biomarkers in NSCLC patients, including ERCC1, BRCA1, hMLH1, hMSH2, RRM1, β-tubulin, TS,EGFR and K-ras, can predict individual patient's response to chemotherapy or targeted therapy, making individualized therapy be possible.
