S-1 in advanced gastric cancer treatment
10.3760/cma.j.issn.1673-422X.2011.04.015
- VernacularTitle:S-1治疗进展期胃癌的研究进展
- Author:
Meiqin YUAN
;
Haijun ZHONG
;
Yunshan YANG
- Publication Type:Journal Article
- Keywords:
Drug therapy;
S-1;
Clinical trials
- From:
Journal of International Oncology
2011;38(4):289-291
- CountryChina
- Language:Chinese
-
Abstract:
S-1 is an upgraded product of tegafur and UFT. Compared with 5-FU, it has stronger anticancer activity, and relative rare gastrointestinal adverse reaction. Many clinical studies have demonstrated S-1 has very good efficacy and safety in patients with advanced gastric cancer. The efficacy of single S-1 has been approved better than other available anti-cancer drugs in the treatment of gastric cancer, and similar to combination regimens such as cisplatin plus fluorouracil.