Crush syndrome in children and the blood purification treatment
10.3760/cma.j.issn.1673-4912.2011.02.005
- VernacularTitle:儿童挤压综合征的血液净化治疗
- Author:
Zheng WANG
;
Yannan GUO
- Publication Type:Journal Article
- Keywords:
Crush syndrome;
Blood purification treatment;
Children
- From:
Chinese Pediatric Emergency Medicine
2011;18(2):113-115
- CountryChina
- Language:Chinese
-
Abstract:
In the recent years,the earthquake occured frequently in the whole world which caused the increased incidence of crush syndrome (CS). The four limbs and torso will be bleeding and swelling when they are prounded and crushed from the heavy objects. The necrosis of muscular tissue causes massive production of toxin which leads to a series of symptoms including hypotension ,kidney dysfunction and so on. The serious acute kidney injury (AKI) will be vital. When CS-AKI ,the ascending velocity of urea nitrogen and K+ levels in the blood is quicker than those of general AKI;many kinds of immune cells are activated to engender a great deal of inflammatory mediators;the blood dynamics is often unstable. Therefore, it is advocated that the blood purification treatment should be carried early to eliminate excessive metabolic produces in vivo,to reduce the cardiovascular complication occurrence, and to avoid the irreversible change of the kidney function.