Risk factors of neurogenic pulmonary edema in the patients with severe hand, foot and mouth disease
10.3760/cma.j.issn.1673-4912.2011.01.010
- VernacularTitle:重症手足口病并发神经源性肺水肿的危险因素分析
- Author:
Zhifang LI
;
Yufen LI
;
Jinsheng LIU
;
Shaoxia SUN
;
Xingfu WU
;
Liyun XU
- Publication Type:Journal Article
- Keywords:
Severe hand-foot-mouth disease;
Neurogenic pulmonary edema;
Risk factors
- From:
Chinese Pediatric Emergency Medicine
2011;18(1):27-29
- CountryChina
- Language:Chinese
-
Abstract:
Objective To understand the risk factors of neurogenic pulmonary edema in the patients with severe hand foot and mouth disease(HFMD). Methods According to neurogenic pulmonary edema or not ,79 patients with severe HFMD were divided into two groups. The difference was analyzed on the clinical symptoms, signs,the outcomes of laboratory and electroencephalogram (EEG) examination between the two groups. Then the risk factors of neurogenic pulmonary edema was analyzed by logistic regression analysis.Results There were significant differences of the EV71 infection rate,high body temperature,myoclonia,limb weakness,the disability of eyeball regulation,tachycardia, hypertension or hypotension, the extension of capillary filling time, leucocytosist, creatine kinase isoenzyme, hyperglycaemia between two groups. However, there were no significant differences of fever, fever time, vomiting, somnolence, convulsion, limb tremor, c-reactive protein and EEG between two groups. Tachycardia, hypertension or hypotension, hyperglycaemia were significant risk factors for neurogenic pulmonary edema by logistic regression analysis. And hyperglycaemia was the most significant prognostic factor(odd ratio 27. 075, P = 0. 000 2). Conclusion Tachycardia, hypertension or hypotension,hyperglycaemia are the significant risk factors for neurogenic pulmonary edema. It is especially important for hyperglycaemia to predict neurogenic pulmonary edema.
