Correlation analysis of macular thickness with optical coherence tomography and visual function in diabetic macular edema
10.3760/cma.j.issn.1673-4904.2011.09.005
- VernacularTitle:光学相干断层扫描定量糖尿病性黄斑水肿的黄斑厚度及与视功能相关分析
- Author:
Lijun JI
;
Xingwei WU
;
Junfang LIANG
;
Jingying SUN
;
Jun RONG
- Publication Type:Journal Article
- Keywords:
Tomography,optical coherence;
Diabetic retinopathy;
Macular degeneration
- From:
Chinese Journal of Postgraduates of Medicine
2011;34(9):12-14
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical features of diabetic macular edema (DME) with optical coherence tomography (OCT) and correlation with visual function. Methods Forty-nine eyes from 40 patients with DME (DME group) and 31 eyes from 31 patients without DME (control group) were examined with OCT,pattern reversal visual evoked potentials (P-VEP),macular perimetry. According to proliferative diabetic retinopathy (PDR), 49 eyes with DME were divided into group A (without PDR, 30eyes) and group B (with PDR, 19 eyes). Results The retinal macular thickness of central fovea in DME group [(299.25±63.87)μm] was more than that in contol group [(204.35 ± 37.94)μm], visual acuity and macular visual field in DME group were significantly different than those in control group, respectively (P ＜ 0.05). The retinal macular thickness of central fovea,visual acuity and visual field were no significant differences between group A and group B (P＞0.05). OCT macular thickness and visual correlation coefficient was -0.437(P＜ 0.05 ); OCT macular thickness and mean defect correlation coefficient was 0.441(P ＜ 0.05). Conclusions OCT can provide a useful tool for monitoring the occurrence and development of DME, can assess the response to treatment. With increasing of the macular retinal thickness, the visual acuity and macular visual field of visual function are more damaged.
