Research of postoperative epidural analgesia for sufentanil combined with ropivacaine under lower limb surgery in elderly
10.3760/cma.j.issn.1673-4904.2011.12.004
- VernacularTitle:舒芬太尼联合罗哌卡因在高龄患者下肢手术术后镇痛的研究
- Author:
Jiehua FENG
;
Chaoyang LI
;
Dong WU
;
Jie AO
;
Jingjing MU
;
Xiaomin LUO
- Publication Type:Journal Article
- Keywords:
Sufentanil;
Ropivacaine;
Aged;
Analgesia,epidural
- From:
Chinese Journal of Postgraduates of Medicine
2011;34(12):8-10
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the safty and proper concentration of using the sufentanil combined with ropivacaine in patient-controlled epidural analgesia (PCEA) under lower limb surgery in elderly. Methods Eighty patients scheduled for lower limb surgery were divided into 4 groups by random digits table with 20 cases in each. The concentration of the sufentanil were 0.1,0.2,0.3 and 0.4 μ g/ml in group A, B, C, D respectively. The concentration of the ropivacaine were 0.125% in each group for the PCEA.R-VAS, C-VAS , Bromage score, Ramsay score, press times ,dosage and side effects were monitored and recorded at 4,10,24 and 48 h after operation. Results Compared with those in group C, D, C-VAS,dosage of the analgesia,press times of PCEA were higher in group A,B (P＜0.01 or ＜ 0.05),the efficacy of press was lower in group A, B(P＜0.05), but there was no significant difference between group C and group D(P＞0.05 ).The Ramsay score 10,24 h after operation in group D[(4.5 ± 0.5 ), (4.6 ± 0.6) scores] was higher than that in group A,B,C [(2.7 ±0.8), (2.7 ±0.8) scores vs.(2.9 ± 0.9), (2.7 ± 0.9) scores vs. (3.0 ±0.7), (2.9 ±0.5) scores] (P ＜0.05). There were no case with hypotension and respiratory depression.Conclusion PCEA of four methods are safe and effective in elderly which 0.3 μ g/ml sufentanil combined with 0.125% ropivacaine have good analgesic effect and less side effect.
