Study on the correlation between serum homocysteine levels with pediatric idiopathic epilepsy
10.3760/cma.j.issn.1008-6706.2011.04.016
- VernacularTitle:血清同型半胱氨酸与小儿特发性癫痫的相关性研究
- Author:
Yun LIU
;
Lijun WANG
;
Mingqing HAN
- Publication Type:Journal Article
- Keywords:
Homocysteine;
Pediatric,idiopathic,epilepsy
- From:
Chinese Journal of Primary Medicine and Pharmacy
2011;18(4):468-470
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo study the clinical significance of determination on homocysteine in serum of pediatric idiopathic epilepsy. MethodsThe homocysteine level in serum of 81 patients with pediatric idiopathic epilepsy was determined,and the value of normal children was tested and compared as control. ResultsThe concentration of Hey in research group was from 7.6mol/L to 22.0μmol/L,the mean value was(15.91 ±2.38)μmol/L,The concentration of Hcy in control group was from 3μmol/L to 9μmol/L,and the mean value was(6.87 ± 1.75)μmol/L.which showed a significant difference(P＜0.05).By comparison,the high concentration(＞15 μmol/L)of Hcy in control group was only 6 cases,while it was 73 cases in research group,which also showed a significant difference (P＜0.05). ConclusionHcy level was apparently relevant with occurring rate of pediatric idiopathic epilepsy.In the diagnosed clinical treatment of idiopathic epilepsy,the closely monitor of serum level of homocysteine,and timely promoting Hcy metabolism.should be carried out.
