Comparison of the effects of propofol combined with remifentanil in different ratios for intravenous anesthesia
10.3760/cma.j.issn.1008-6706.2011.04.030
- VernacularTitle:丙泊酚联合瑞芬太尼不同配比用于静脉全身麻醉的效果比较
- Author:
Xiaoya YE
;
Bingquan LU
- Publication Type:Journal Article
- Keywords:
Propofol;
Remifentanil;
General anesthesia
- From:
Chinese Journal of Primary Medicine and Pharmacy
2011;18(4):500-502
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo explore the effects of propofol combined with remifentanil in different ratios for intravenous anesthesia. Methods63 patients were randomly divided into three groups,each group 21 cases,different target plasma concentration of propofol and remifentanil were dosed for every group.Hemodynamic parameters such as MAP,HR were recorded at different time.so as to stop time for the zero time of local anesthetic.The extubation time,the quality and time of awakening were compared as well. ResultsThe MAP and HR value of all patients after induction of general anesthesia were lower than that before intubation,which showed significant difference(all P＜0.05),and the MAP and HR value of all patients after intubation reseal and decannulation showed significant difference compared with that before intubation reseal.The resurgence time and decannulation time of group A were the shortest,and the postoperative detubation revive quality score was also the best when compared with that of group B and C. ConclusionThe target plasma concentration of propofol(2.5mg/L)and remifentanil(μg/L)was the best.With the increasing of target plasma concentration of remifentanil and the decreasing of target plasma concentration of propofol,the resurgence time,decannulation time and the postoperative detubation revive quality score were improved gradually.
