The Analysis for Macrovascular Disease in Newly Diagnosed Type 2 Diabetic Patients
10.3760/cma.j.issn.1008-6706.2011.04.008
- VernacularTitle:初诊2型糖尿病患者大血管病变的危险因素分析
- Author:
Yue GAO
;
Ping YU
;
Jiali WU
;
Li LI
;
Fengming ZHENG
;
Liyan ZHU
- Publication Type:Journal Article
- Keywords:
Diabetes mellitus type 2;
Macrovascular disease;
Risk factor
- From:
Chinese Journal of Primary Medicine and Pharmacy
2011;18(4):450-452
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo investigate the risk factors associated with macrovascular disease in patients with newly-diagnosed type 2 diabetes. MethodsAccording to arterial intima-media thickness(IMT)measured by color duplex ultrasonography,232 cases of newly-diagnosed type 2 diabetic patients were divided into two groups:one group were 95 cases with macrovascular disease(MD),and the other group were 137 cases without macrovascular disease (non-MD).Then various clinical data between the two groups were compared and the correlated risk factors for macrovascular disease were analyzed. Results (1)95 patients(40.9%)showed macrovascular disease in 232 patients.(2)Age,BMI,SI,systolic blood pressure,diastolic blood pressure,TC,LDL-C,CRP and 24h UmAlb were significantly higher in MD group compared with those in non-MD group(all P<0.05);But ISI was significantly lower in MD group compared with that in non-MD group(P<0.05).(3)Pearson correlation analysis showed that risk factors were old age,BMI,smoking,higher systolic blood pressure,higher diastolic blood pressure,TC,LDL-C,CRP and microalbuminuria. ConclusionMacrovascular disease was related to many factors.It was important to control some risk factors earlier for preventing the happening and progress of macrovascular disease.