The research of carotid atherosclerosis and its relative factors of maintenance peritoneal dialysis patients
10.3760/cma.j.issn.1008-6706.2011.05.007
- VernacularTitle:维持性腹膜透析患者颈动脉硬化及相关因素分析
- Author:
Junfu XU
;
Qun LUO
- Publication Type:Journal Article
- Keywords:
Peritoneal dialysis;
Atherosclerosis;
Inflammation;
Malnutrition
- From:
Chinese Journal of Primary Medicine and Pharmacy
2011;18(5):590-592
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore carotid atherosclerosis and its relative factors of maintenance peritoneal dialysis patients. Methods The general clinical conditions,hematobiochemical parameters and color ultrasound parameters of 27 maintenance peritoneal dialysis patients and 24 controll patients were collecled. General clinical conditions included body weight, height and BMI. Hematobiochemical paremeters included Hb, Alb, LP (a), TC, TG, HDL-C,LDL-C, CRP, plasma fibrinogen, C3, Apo-A 1, Apo-B, LP (a). Color ultrasound parameters included plaque incidence rate,thickness of vascularendothelium(IMT). Results Compared with the controll group,maintenance peritoneal dialysis patients: plaque incidence rate, thickness of vascularendothelium (IMT) increased significantly, Age, TC, TG,LDL-C,LP (a), dialysis time increased significantly in plaque-positive group(all p ＜ 0. 05), while Hb, Alb andPAB decreased significantly (all P ＜ 0.0 5) , CRP increased significantly (P ＜ 0.0 1) . Conclusions In maintenance peritoneal dialysis group,CRP,LP(a) had positive relationship with C-IMT. CRP had negative relationship with ALb. CRP had not relationship with age and dialysis time. There were relationships among malnutrition,inflammation and atherosclerosis in maintenance peritoneal dialysis patients. Interdiction of the relationship may played a very important role in ameliorating the prognosis of the maintenance peritoneal patients.
