A study of serum interleukin 6 and interleukin 18 in acute coronary syndrom patients with type D personality
10.3760/cma.j.issn.1674-6554.2011.02.009
- VernacularTitle:D型人格急性冠脉综合征患者血清IL-6、IL-18水平研究
- Author:
Shue NING
;
Peng QU
;
Gang WEI
;
Meili ZHENG
;
Zheng SUI
;
Dafei ZONG
;
Xing ZHANG
- Publication Type:Journal Article
- Keywords:
Type D personality;
Acute coronary syndromes;
Prognosis;
Interleukin 6;
Interleukin 18
- From:
Chinese Journal of Behavioral Medicine and Brain Science
2011;20(2):122-124
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore what kind of role serum interleukin 6 (IL-6) and interleukin 18 ( IL-18) play in the relationship between type D personality and acute coronary syndrom (ACS)prognosis.Methods Serum levels of IL-6,IL-18 in all 214 ACS patients were measured with ELISA.According to the scores of type D personality scale(DS14) ,the subjects were divided into the group with type D personality (50 cases)and the one without type D personality ( 164 cases).The serum IL-6 and IL-18 level between the two groups were detected and analyzed.Results There were 23.36% ACS patients with type D personality.The serum IL-6, IL-18levels of the group with type D in ACS acute stage and ACS recovery stage were (2.340 ± 0.081 )OD, (2.016 ±0.023 ) OD and ( 1.460 ± 0.070 ) OD, ( 1.313 ± 0.012 ) OD respectively, significantly higher than those of the group without type D (2.178 ± 0.180)OD, ( 1.849 ± 0.159)OD and ( 1.387 ± 0.091 )OD, ( 1.196 ± 0.132 ) OD respectively(P＜0.01).Conclusion At home and abroad ,there are similar amount of ACS patients with type D personality.The high serum IL-6 and IL-18 levels may play an important role in pathogenesis of relationship between type D personality and ACS poor prognosis.
