The value of MR in the diagnosis of primary splenic lymphoma
10.3760/cma.j.issn.1008-6706.2011.03.031
- VernacularTitle:磁共振检查对脾脏淋巴瘤的诊断价值
- Author:
Haiyang NI
;
Rui ZHANG
;
Jinghong LU
;
Jingqiu WANG
;
Hongsheng CUI
;
Xuefeng ZHAO
- Publication Type:Journal Article
- Keywords:
Splenic neoplasms;
Lymphoma;
Magnetic resonance spectroscopy
- From:
Chinese Journal of Primary Medicine and Pharmacy
2011;18(3):349-350
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the value of MR in the diagnosis of primary splenic lymphoma (PSL).Methods The MR imaging features of 3 PSL cases proved by pathology were retrospectively reviewed. Results Three cases were all pathologically diagnosed as B-cell non-Hodgkin's lymphoma(NHL). Two cases were multiple node shape and one was massive shape. Unenhanced MR imaging revealed heterogeneous splenic enlargement, with large nodules showing iso-hyperinternse on T1WI and hypointense on T2WI. Linear hyperintense on T1WI and T2WI was seen on the spleen peripherous. The spleen vascular was infiltrated. CE-MRI showed heterogeneous enhancement of spleen with iso-hypointense. The focus of postperitoneal showed medial enhancement. Immunohistochemistry-showed 2 cases of diffuse B cell. The CD20 and CD19 α of tumor cell showed diffuse( + ) ,CD3 ,CD5 individual( + ) ,CD43 ( + ) ,CD45RO( + ), CD10 ( +/- ), Mum ( + ), MAC387 individual ( + ), 1 case of B lymphocell type, CD79α ( + ) ,CD23( + ) ,CD38( + ) ,λ( + ). Conclusion The MR imaging features of PSL were characteristic and helpful in the diagnosis of PSL, but the correct diagnosis was still dependent on the pathology and immunohistochemical staining.
