Clinical significance of the changes of serum IL-6, IL-8,TNF-α and CRP in perioperative patients with pancreatitis
10.3760/cma.j.issn.1008-6706.2011.03.011
- VernacularTitle:胰腺炎患者围术期血清肿瘤坏死因子-α、白细胞介素-6、-8及C反应蛋白水平变化及意义
- Author:
Jinguo TIAN
;
Yudong JIA
;
Haitao LIU
- Publication Type:Journal Article
- Keywords:
Pancreatitis;
Perioperative;
IL-6;
IL-8;
TNF-α;
CRP
- From:
Chinese Journal of Primary Medicine and Pharmacy
2011;18(3):309-310
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the variation of serum IL-6,IL-8,TNF-α and CRP in perioperative patients with pancreatitis. Methods 39 caaes in perioperative patients with pancreatitis in our hospital from January 2008 to 2010 April were selected as observation group,and 39 healthy people were selected as control group,and the serum IL-6,IL-8,TNF-α and CRP of the observation group before the treatment and after the treatment at 4h,at the first day, at the second day and the seventh day and the control group were detected, and the results were analyzed and compared. Results The serum IL-6,IL-8 ,TNF-α and CRP of the observation group before the treatment were higher than those of the control group( all P ＜ 0. 01 ) there were significant differences, and the levels of the observation group at 4h,at the first day,and at the second day showed decreasing,the levels compared to those of the control group( all P ＜ 0. 05 ) there were significant differences, the levels of the observation group at seventh day were compared to those of the control group(all P＞0. 05) there were no significant differences. Conclusion It was regulation of the variation of serum IL-6, IL-8 ,TNF-α and CRP in perioperative patients with pancreatitis, and tit could provide evidence for the treatment.
