A study on autonomic nerve function of coronary heart disease patients with panic disorder
10.3760/cma.j.issn.1674-6554.2011.03.017
- VernacularTitle:冠心病合并惊恐障碍患者自主神经功能的研究
- Author:
Zhaojun CHEN
;
Xishan YANG
;
Pingshuan DONG
;
Zhijuan LI
;
Ke WANG
- Publication Type:Journal Article
- Keywords:
Coronary heart disease;
Panic disorder;
Heart rate variability;
Autonomic nervous function
- From:
Chinese Journal of Behavioral Medicine and Brain Science
2011;20(3):247-249
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the changes of autonomic nerve function of coronary heart disease (CHD) patients with panic disorder(PD). Methods All the subjects who met with the diagnostic code of CHD and PD were divided into CHD group(n=40) ,PD group(n=36) ,comorbid CHD and PD group(n=27) ,and 40physical examinee were recruited as normal control group. They had a 24 hours Holter ECG monitoring by time and frequency domain analysis of heart rate variability. ANOVA analysis was utilized to statistic the collected data. Results Compared with normal controls,the patients of others groups had every indexs of HRV were reduced. The indexs of HRV of comorbid CHD and PD were lower than the patients of CHD or PD group. The score of time domain SDNN(70.40 ± 14.74)ms,SDANN(91.72 ± 24.46)ms,PNN50(2.83 ±2.07)%, RMSSD( 15.66 ±7.45)ms,frequency domain LF(647.54 ± 129.24)ms2, HF(596. 16± 127.66) ms2 in comorbid CHD and PD. There were significant differences with others groups(P ＜ 0.05 ). Conclusion The autonomic nervous functional of the patients with CHD and PD were in disorder. The autonomic nervous functional disorder of the patients with comorbid CHD and PD was more severe.
