Association study between early trauma experience and obsessive-compulsive disorder
10.3760/cma.j.issn.1674-6554.2011.01.003
- VernacularTitle:早年创伤经历与强迫症的相关性研究
- Author:
Xuemei WANG
;
Zhen WANG
;
Haiting XU
;
Zeping XIAO
- Publication Type:Journal Article
- Keywords:
Obsessive-compulsive disorder;
Early trauma;
Yale-brown obsessive-compulsive severity scale(Y-BOCS );
Early trauma inventory self report-short form (ETISR-SF)
- From:
Chinese Journal of Behavioral Medicine and Brain Science
2011;20(1):7-9
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the association between early trauma experiences and obsessivecompulsive disorder (OCD). Methods One hundred and eighty-five patients who met with OCD diagnosis of DSM-Ⅳ and one hundred and thirty-two healthy controls were recruited. Early trauma experience of all participants was assessed with Early Trauma Inventory-Short Form (ETI-SF) ,and severity of symptoms of OCD patients was evaluated with Yale-Brown Obsessive-Compulsive Severity Scale (Y-BOCS). Results When compared with controls, OCD group showed significantly higher in ETI-SF total score (3.55 ± 3.29 vs 1.51 ± 1.98, P ＜ 0. 01 ) and had greater in general trauma (0.89 ± 1.10 vs 0. 43 ±0.77, P＜0.01 ) ,physical abuse (0.98 ± 1.31 vs 0.65 ±1.04, P=0. 016),emotional abuse(1.43 ±1.61 vs 0.38 ±0.89, P＜0. 01),and sexual abuse(0.24 ±0.59 vs 0.06 ±0.30, P＜0. 01 ). Female OCD patients reported more sexual abuse than male patients(0.33 ±0.69 vs0. 16 ± 0.45, P = 0.049) . There was a negative correlation between onset age of obsessive symptoms and early trauma experiences(P ＜ 0. 01 ), except sexual abuse experiences (P = 0. 10). Conclusion OCD patients have much more childhood traumas, and the more trauma experiences are,the earlier onset of OCD is, which may associated with the development of obsessive-compulsive disorder.
