Analysis of clinical features and treatment of patients with severe type A H1N1 flu in Wenzhou
10.3760/cma.j.issn.1000-6680.2011.02.010
- VernacularTitle:温州地区重症甲型H1N1流行性感冒的临床特征与治疗分析
- Author:
Xiangao JIANG
;
Jichan SHI
;
Haiyan ZHU
;
Feifei SU
;
Xiaoya CUI
;
Hongye NING
;
Shoufeng YANG
;
Fangping JIN
- Publication Type:Journal Article
- Keywords:
Influenza A virus,H1N1 subtype;
Influenza,human;
Critical illness;
Oseltamivir;
Antiviral agents
- From:
Chinese Journal of Infectious Diseases
2011;29(2):113-115
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical features and effective treatment of patients with severe type A H1N1 flu in Wenzhou. Methods The clinical data of 42 hospitalized patients with severe type A H1N1 flu were analyzed and the clinical features were summarized. Results A total of 42 patients with severe type A H1N1 flu all began with fever and cough. The symptoms of expectoration, pharyngalgia, chilly accounted for 92. 9%, 90. 5% and 42. 9%, respectively. The peripheral leucocyte counts were normal or reduced. C-reactive protein and erythrocyte sedimentation rate levels both increased in 30 patients (71.4%). About 95.2% (40/42) patients had changes of pulmonary imaging. All of the patients were treated with oseltamivir and effective antibiotic drugs as well as symptomatic management. No patients was treated with glucocorticoid. The patients with underlying diseases were given proper treatment. Three cases were treated with antifungal therapy and 3 pregnant patients were timely terminated of pregnancy. Conclusions Severe type A H1N1 flu progresses rapidly and the lower respiratory tract is involved soon after onset. Therefore, the patient should be diagnosed early and treated promptly after presenting fever, which will lead to good prognosis.
