In vitro bacterial resistance monitoring of urinary tract infectious in female elderly patients
10.3760/cma.j.issn.1008-6315.2011.03.014
- VernacularTitle:老年女性糖尿病患者尿路感染病原菌的体外耐药性监测
- Author:
Guangling LIN
;
Linxing CHEN
;
Meishan LIN
;
Hongni GU
;
Bo LIU
- Publication Type:Journal Article
- Keywords:
Diabetic;
Urinary tract infection;
Drug resistance monitoring
- From:
Clinical Medicine of China
2011;27(3):264-266
- CountryChina
- Language:Chinese
-
Abstract:
Objective To determine the distribution and antibiotics resistance characteristic of pathogens in urinary tract infections in aged female diabetics patients and provide scientific basis for clinicians in selecting effective antibiotics. Methods Pathogenic bacteria, isolated from specimens of 107 elderly female diabetic cases with urinary tract infections, were identified and drug susceptibility tests were performed by VITEK-32 analysator. Results Among all 107 kinds of isolated bacteria,the ratio of gram-negative bacteria was 74. 8% ( 80/107 ), predominated by Escherichiacoli ( accounting for 48. 6% [52/107] ); the ratio of gramposition bacterias was 13. 1% (14/107) and eumycetes was 12. 1% (13/107). In antibiotic resistance analysis,the gram negative bacteria showed higher drug-resistance to the some common-antibiotics, such as ampicililin,cefazolin,cefuroxime-sodium and cefuroxime axetil ( ＞ 70. 0% ), while they were sensitive to imipenem and amikacin( ＜ 10. 0% ). The gram positive bacteria were most sensitive to vancomycin (0%), followed by Linezolid(7.7% ). Conclusion Escherichiacoli were the major pathogenic bacteria in urinary tract infections in aged female diabetic patients, with higher drug resistance. Therefore, drug resistance monitoring should be carried out according to the variety of pathogenic bacteria so as to guide rational use of antibiotics and decrease drug resistance.
