Clinical significance of myocardial Toponin Ⅰ in children obstructive sleep apnea-hypopnea syndrome
10.3760/cma.j.issn.1008-6315.2011.03.039
- VernacularTitle:心肌肌钙蛋白Ⅰ在阻塞性睡眠呼吸暂停低通气综合征患儿中的意义
- Author:
Cong LIU
;
Jun WANG
;
Xiangyi LIU
- Publication Type:Journal Article
- Keywords:
Obstructive sleep apnea-hypopnea syndrome;
Tropnin Ⅰ;
Children;
Myocardial damage
- From:
Clinical Medicine of China
2011;27(3):328-329
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the risk of myocardial damage induced by obstructive sleep apneahypopnea syndrome (OSAHS) in children. Methods Twenty-three children who were in-hospital patients and diagnosed as adenoidal hypertrophy or palatine tonsil hypertrophy enrolled in the study as cases,among whom 15cases were affected by OSAHS (OSAHS group) ,and 8 cases were not affected by OSAHS( no-OSAHS group).Twenty-seven healthy children from health physical examination were enrolled as controls (control group).Chemiluminescence was used to detect the value of Troponin Ⅰ (TnⅠ) in all children, and the values of the three groups were compared. Results In the OSAHS group, TnⅠ was (0. 022 ± 0. 009) μg/L;in the non-OSAHS group, TnⅠ was (0.035 ± 0.012) μg/L;in the control group,TnⅠ was (0.017 ± 0.015) μg/L. There were significant difference among the three groups ( F = 8. 369, P = 0. 001 ). Furthermore, compared with the control group,TnI in the OSAHS was significantly higher( P ＜ 0. 001 ). Conclusion Children with adenoid or tonsil hypertrophy associated with OSAHS in children were found to have myocardial damage compared to healthy children, whereas similar on myocardial damage to children with adenoid and tonsil hypertrophy but not OSAHS.
