Study of relationship between myocardial infarction size and left ventricular torsion by speckle tracking imaging
10.3760/cma.j.issn.1004-4477.2011.03.023
- VernacularTitle:斑点追踪显像技术评价心肌扭转与心肌梗死范围相关性的实验研究
- Author:
Zhiming WU
;
Xianhong SHU
;
Junqing SHI
;
Lili DONG
;
Cuizhen PAN
;
Bing FAN
;
Shaoliang CHEN
- Publication Type:Journal Article
- Keywords:
Echocardiography;
Myocardial infarction;
Torsion;
Speckle tracking imaging
- From:
Chinese Journal of Ultrasonography
2011;20(3):249-252
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the most sensitive markers of left ventricular(LV) torsion which can reflect infarct size by assessing the relationship between routine markers of LV torsion and infarct size using speckle tracking imaging (STI).Methods Fifteen open-chest pigs underwent 120 minutes of left anterior descending (LAD) ligation followed by 12 hours of reperfusion.Rotation and torsion of LV were obtained by STI before LAD occlusion,LAD occlusion immediately,and 30,60,90 minutes and 12 hours after reperfusion.Infarct size was measured by nitrotetrazolium blue chloride staining.Results LAD ligation resulted in a dramatic decrease in both subepicardial and subendocardial peak apical rotation or peak LV torsion.Twelve hours after reperfusion,all of the peak rotation and torsion remained significantly reduced (P ＜ 0.01 versus AMI).At AMI,peak bulk LV torsion and peak bulk apical rotation inversely correlated with infarct size (r = - 0.81,P ＜0.01; r = - 0.69,P ＜0.01).There existed the good relationship at 12-hour follow-up after reperfusion.The relationship was superior to that of other torsion markers.Conclusions Peak bulk LV torsion and peak bulk apical rotation are the most sensitive markers of LV torsion which can reflect infarct size.
