The preliminary clinical study in liver lesions'movement and impact factors
10.3760/cma.j.issn.1004-4221.2011.02.019
- VernacularTitle:肝脏占位性病变的运动规律及其影响因素的初步临床研究
- Author:
Yongchun SONG
;
Liming XU
;
Zhiyong YUAN
;
Wei WANG
;
Xiuying LI
;
Ying ZHU
;
Ping WANG
- Publication Type:Journal Article
- Keywords:
Liver lesion;
Distance of displacement;
Influencing factors
- From:
Chinese Journal of Radiation Oncology
2011;20(2):153-155
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the movement,and the factors that influence such movement of liver lesions and to provide a reference for determination of internal target volume (ITV) during stereotactic radiotherapy. Methods We implanted 1 -2 gold markers into or near the liver tumors of 42 liver primary or metastasis cases percutaneously under B-ultrasound or computer tomography (CT) guidance. The marked motion of liver lesions in x ( right-left), y (superior-inferior) and z (anterior-posterior) directions was measured via X-ray simulator system. Based on the statistical analysis of the detected movements, we investigated the relevant influencing factors of liver lesions with bivariate correlation analysis. Results Data showed that mean motion amplitudes of liver lesions were 0.27 ± 0. 11 cm (0. 1 -0. 5cm) in x direction,0.38 ±0. 19 cm (0. 1 -0. 8cm) in y direction and 1.19 ±0. 27 cm (0. 5 - 1.9cm) in z direction. Motion amplitude was not correlated with the height, weight or age of the patients nor with the location or size of the tumor. Conclusions Motion of liver lesions was mainly influenced by the respiratory and has maximal amplitude in the z direction. Therefore,the motion in the z direction should be given a priority consideration while determining the ITV.
