Comparison between Willis covered stent placement and coil embolization in the treatment of cranial internal carotid artery aneurysm: a nonrandomized prospective trial
10.3760/cma.j.issn.1005-1201.2011.02.020
- VernacularTitle:Willis覆膜支架与弹簧圈栓塞治疗颅段颈内动脉瘤效果的比较
- Author:
Zhenkui SUN
;
Yongdong LI
;
Binxian GU
;
Minghua LI
;
Huaqiao TAN
;
Wu WANG
;
Donglei SONG
;
Bing LENG
;
Jue WANG
;
Peilei ZHANG
- Publication Type:Journal Article
- Keywords:
Intracranial aneurysm;
Embolization,therapeutic;
Coil;
Stent;
Case-control studies
- From:
Chinese Journal of Radiology
2011;45(2):183-188
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinical results of Willis covered stent implantation and coil embolization in the treatment of cranial internal carotid artery (CICA) aneurysm. Methods Eighty-nine patients with CICA aneurysms were selected for treatment with Willis covered stents (n = 43, group A) or coil embolization (n =46, group B) according to the patients'will. Data on the technical success, initial procedure time and in-hospital interval, initial and final angiographic results, mortality, morbidity, and final clinical outcomes were collected and analyzed for the two groups at 6 months post-procedure. Results Endovascular covered stent placement and coil embolization were technically successful in all patients,except for one patient in group A. The initial angiographic results showed complete occlusion in 34 patients of group A (81%, 95% CI: 69%, 93% ) and 24 patients of group B (52%, 95% CI: 37%, 67% ) ( P ＜0. 05). The final angiographic results indicated complete occlusion in 39 patients of group A (39/41,95%,95% CI: 88%, 102% ) and 22 patients of group B (22/45,49%, 95% CI: 34%, 64% ,P ＜0. 01 ). The average procedure time was(103 ± 13)min in group A and (143 + 39) min in group B (P＜0. 01). No significant differences were seen between the two groups in technique success, mortality, morbidity, or final clinical outcomes. Conclusion In this nonrandomized, prospective trial, CICA aneurysm treatment with covered stents yielded midterm angiographic results that were superior to those of coil embolization.
