Paraganglioma of urinary bladder (two cases reports and review of literatures)
10.3760/cma.j.issn.1000-6702.2011.03.018
- VernacularTitle:膀胱副神经节瘤二例报告并文献复习
- Author:
Min FAN
;
Xiaozhou HE
;
Xianlin XU
;
Renfang XU
;
Zhifu CHAO
;
Wei XIA
;
Tongbing CHEN
;
Chunyin YAN
- Publication Type:Journal Article
- Keywords:
Urinary bladder neoplasms;
Paraganglioma;
Pathology,clinical
- From:
Chinese Journal of Urology
2011;32(3):199-202
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the clinical,histopathological,immunohistochemical features and the diagnosis and treatment of paraganglioma of urinary bladder. Methods Two cases of paraganglioma of urinary bladder were treated. The first case was a male with painless haematuria. The abdominal ultrasonography and CT scan showed a 2.5 cm× 2.0 cm mass in the right anterior wall of the bladder, and urine vanillylmandelic acid elevated to 17. 9- 31. 3 μmol/24 h (normal range 10- 35 μmol/24 h). The second case was a female who presented with 8 years history of headache and palpitation after voiding. Abdominal ultrasonography and CT scan showed a 2. 6 cm× 1.5 cm mass in the left wall of the bladder, and her urine vanillylmandelic acid was 35.3-43.3 μmol/24 h. Results One patient underwent transurethral resection (TURBT) and the other underwent partial cystectomy.The two cases were diagnosed as bladder paraganglioma by pathological examination. Immunohistochemically, the tumor cells were positive for CgA, Syn, NSE and S-100. No evidence of recurrence was detected during follow-up at 3 months and 3 years. Conclusions Paraganglioma of urinary bladder should be considered as a low grade malignancy. Partial cystectomy should be recommended. The diagnosis depends on clinical symptoms, pathological and immunohistochemical results.
