Diagnosis and treament of ovarian germ cell tumors
- Author:
Nguyen Manh Quoc
- Publication Type:Journal Article
- Keywords:
ovarian germ cell tumors
- MeSH:
Ovarian Neoplasms;
alpha-Fetoproteins;
Dysgerminoma;
diagnosis;
therapeutics;
- From:Journal Ho Chi Minh Medical
2003;7(4):207-215
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
In 5 years (1994-1998), 168 patients with ovarian germ cell tumors were diagnosed and treated in HCM city Cancer Hospital. Ovarian germ cell tumor is a rare disease. These tumors were often detected in early stage (61.2% in stage I, among them 39.6% in stage IA). The tumor marker AFP plays an important role in diagnosis and follow-up the disease. AFP was positive in 60% cases of malignant germ cell tumors, among them 55.6% were immature teratomas, and AFP was negative in dysgerminoma. The rate of teratomas was highest: 53%, rate of dysgerminoma: 19%, endodermal sinus tumor 14.9%, embryonal carcinoma 9.5% and mixed forms 3.6%. It’s necessary to emphasize the role of preservative surgery in the treatment of these tumors